How Long Does Creatine Stay In Your System? (Explained)

For those who hold an avid interest in their physical wellness and building muscle mass the concept of creatine is likely not unknown. In the world of fitness and sports, it’s common knowledge that creatine is a natural compound essential for generating energy while working out. Our bodies produce this substance on their own.

The fact that this supplement has become an absolute sensation within the athlete and gym enthusiast community comes with no surprise. After all with its capacity to improve muscle strength increase endurance levels and hasten recovery time has become impossible to overlook.

Those who are interested in supplementing with creatine or currently doing so might be curious about how long it stays in your system. Knowing the ideal timing and regularity of creatine supplement ingestion along with any potential need for discontinuation is a crucial matter.

Delving into the world of fitness supplements can be confusing – especially when it comes to creatine supplements. We’ll answer one of the most pressing questions surrounding its use: “How Long Does Creatine Stay in Your System?”

Discover with us the timeframe for creatine’s presence in your system and any potential implications upon discontinuation. Furthermore, we’ll analyze how different factors can impact this timeline. So, keep reading!

How Long Does Creatine Stay in Your System?

Creatine starts to deplete from the body after 2 weeks but usually stays in the body for around 4-6 weeks after the last intake, although this timeframe can differ based on individual factors. These factors can include frequency of use, age, gender, and metabolism.

Creatine supplements may stay in the system for longer periods in people taking larger doses or with slower metabolisms. Consistent use can lead to a buildup, while infrequent use can result in quicker elimination. Age, weight, exercise routine, and other factors can also influence how long creatine stays in the system. We’ll talk about the factors more in one of the upcoming sections.

One must acknowledge that there is a differentiation between the half-life of creatine and how quickly it is eliminated from the system. Half-life denotes how much time is required for 50% of an individual’s existing creatine levels to decline while clearance time signifies how long it will take for most of this compound within an individual’s system to deplete.

Creatine’s half-life is only around three hours. Upon ingesting five grams worth of creatine supplement approximately half will remain (or roughly 2.5 grams) by the time three hours pass. After another 3 hours, you’ll have approximately 1.25 grams left, and so on.

However, the clearance time of creatine can be much longer, taking up to 2-6 weeks for your body to completely eliminate it depending on different elements.

Now let’s see what existing evidence says:

  1. Based on the findings of a study, approximately 46% of the ingested creatine was excreted in the urine within 24 hours of ingestion. Therefore, it can be assumed that the remaining 54% of creatine is still in the body after 24 hours. However, the study did not provide information on how long the remaining creatine stays in the system beyond the initial 24 hours. [1]
  2. Emerging research has demonstrated an astounding increase in muscle creatine concentration by as much as 20% with a mere six-day usage of just twenty grams per day. Impressively this heightened level remained consistent even when users reverted back to only two grams each day throughout thirty days. After the discontinuation of supplementation, it took around 30 days for the muscle’s creatine concentration to return to baseline. Taking 3 g/day was found to be as effective as 20 g/day in the long term. Therefore, the time creatine stays in the system varies depending on the dose and duration of supplementation. [2]
  1. Another finding reveals that even after stopping the consumption of creatine supplements for an entire month muscle phosphocreatine does not completely revert back to its initial levels. Interestingly plasma and urine concentrations of creatine did reach baseline during this timeframe. It was found that after participants were given their first dose of creatine supplements, their muscle phosphocreatine levels increased by a noteworthy amount- reaching as high as a staggering margin of 45%. Although they later experienced a slight dip during washout periods- roughly around -22%, upon subsequent administration they saw another notable incline on average around an upliftment rate markup ranging up to around +25%. The increased muscle phosphocreatine persisted throughout the 30-day washout period and corresponded with the maintenance of increased body mass (+2.0 kg). Therefore, it can be concluded that creatine can stay in the system for longer than 30 days, and athletes should be aware of this when planning their supplementation regimen. [3]

Related: How Long Does It Take Ashwagandha To Leave Your System?

What Happens if You Stop Taking Creatine?

How long does creatine stay in your system

Creatine supplementation can lead to increased muscle strength and size, but what happens when you stop taking it? When you discontinue creatine use, there may be potential effects on your muscle strength and size. The significance of creatine supplements in enhancing muscle energy production for rigorous workout sessions cannot be overstated. It follows that discontinuing its intake could potentially disrupt optimal performance during high-intensity exercises. This can cause less muscle growth and less strength over time.

Do Creatine Results Go Away?

If you’re wondering whether the results gained from taking creatine will disappear once you stop taking the supplement, the answer is not exactly straightforward. An apparent reduction in your muscular strength and size may occur with discontinuation of creatine supplementation.

This decrease can occur gradually and may not be noticeable right away. The pace at which your body experiences declines in both muscle mass and strength can be attributed to a number of different factors working together. These include lifestyle choices such as diet and exercise habits as well as age. It should be noted that maintaining progress obtained from creatine supplementation requires ongoing dedication toward consistent exercise and healthy eating habits, even following the termination of supplement usage.

Related: Does Creatine Go Bad? How Long Till It Expires?

Factors that Affect Creatine Clearance Time

The clearance time of creatine from the body can vary depending on several factors, such as age, weight, exercise routine, and kidney function. People who carry more weight and have larger muscles may have a longer clearance time than those who weigh less and have smaller muscles. Similarly, older individuals may have a longer clearance time compared to younger individuals, as kidney function declines with age.

The type and intensity of exercise can also affect creatine clearance time. This is because high-intensity exercise can increase blood flow and enhance creatine uptake by the muscles.

Other factors that may affect creatine clearance time include genetics and hydration status. Certain genetic variations can affect how the body processes and eliminates creatine, while dehydration can slow down the clearance process.

It’s essential to acknowledge that these factors may not have a noteworthy impact on how fast certain individuals can remove substances from their systems. Recognizing potential negative outcomes is imperative in comprehending how creatine operates within our system and its persistence over time.

Related: Can You Mix Creatine With Pre Workout? Is It Safe?

How to Flush Creatine from Your Body?

Here are some more ways to flush creatine from your body:

  • Reduce or eliminate creatine supplementation.
  • Increase water intake.
  • Increase cardiovascular exercise.
  • Increase sweat production through sauna use or intense exercise.
  • Optimizing your health can be as simple as incorporating fruits and vegetables into your diet as they are packed with essential water and electrolytes.

While there is no single definitive way to flush creatine out of your system, some methods may speed up the clearance time. It should be emphasized that the effectiveness of these methods can vary and there are potential dangers involved. Therefore consulting a healthcare provider beforehand is integral for safe and optimal outcomes.

A straightforward and effective method for eliminating creatine from your body is through increased water consumption. Staying hydrated can help flush out excess creatine through urine. 

Another way to speed up the clearance of creatine is to perform intense exercises like cardiovascular exercise. Cardiovascular exercise increases blood flow, which can help eliminate creatine from your muscles more quickly.

Remember, creatine supplements mostly are not harmful to your body, and there is no need to rush the clearance process. Your body will eventually eliminate the excess creatine on its own.

Related: Is Creatine Natty (Natural)? The Truth about Creatine

How Long Does Creatine Take to Kick In?

Alexey Koza/iStock

People are often confused by differing opinions on the effectiveness of creatine supplements. The truth is not everyone responds at the same pace – one person might experience results after only a few doses while another requires more than several weeks before any improvements appear visible for them personally. Generally, it takes creatine anywhere from a week to a month to kick in.

Creatine can take a varying amount of time to kick in depending on the individual and the dosage protocol used. However, most people start to see some benefits within a few weeks of starting creatine supplementation.

The loading phase is the period of time during which you take a higher dose of creatine supplements to help saturate your muscles with it more quickly. Typically, during the loading phase, you take 20 grams of creatine per day, divided into four 5-gram doses, for 5-7 days. After that, you can drop down to a maintenance dose of 3-5 grams per day.

Research has shown that the loading phase can help you see results faster than just taking a maintenance dose from the start [4]. 

It’s important to note that the loading phase isn’t necessary, and some people choose to skip it altogether and just start with a maintenance dose. Also, it’s essential to be patient and consistent when taking creatine supplements to see results. 

Don’t expect to see results overnight, but with consistent use, you should start to notice improvements in muscle strength, endurance, and size. 

Related: Can You Dry Scoop Creatine? Yes, But There’s a Catch



Athletes and bodybuilders frequently seek ways to improve their performance through supplements like creatine. This popular option boasts benefits that aid in athletic capabilities while encouraging muscle development. It is important to note that factors like usage amounts or frequency levels are taken into account when considering how long it stays in the system based on metabolic speeds or physical activity patterns.

Here are the main takeaways from this article:

  • When taken appropriately and within limits, Creatine is considered a harmless and efficient supplement.
  • Creatine has a half-life of roughly three hours meaning it takes that long for half of the ingested substance to be flushed from the body. However, it’s possible for creatine to stay within the system for several weeks.
  • Factors that affect how long creatine stays in the system include dosage, frequency of use, individual metabolism, and exercise habits.
  • Drinking plenty of water and engaging in regular exercise can help flush creatine out of the system more quickly.
  • Prioritizing safety when considering the use of any supplement, including creatine necessitates consulting with a healthcare provider.

Knowing how creatine supplements operate within the body proper dosing protocols and duration of use are key to achieving desired outcomes without adverse effects.

More Creatine Guides

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Should I Take Creatine While Trying To Lose Belly Fat?

Nighttime Creatine: Can You Take Creatine Before Bed?

Flying High: Can You Bring Creatine On A Plane?

Does Creatine Break a Fast? Unlocking the Truth

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  1. Burke DG, Smith-Palmer T, Holt LE, Head B, Chilibeck PD. The effect of 7 days of creatine supplementation on 24-hour urinary creatine excretion. J Strength Cond Res. 2001 Feb;15(1):59-62. PMID: 11708707.
  2. Hultman E, Söderlund K, Timmons JA, Cederblad G, Greenhaff PL. Muscle creatine loading in men. J Appl Physiol (1985). 1996 Jul;81(1):232-7. doi: 10.1152/jappl.1996.81.1.232. PMID: 8828669.
  3. Rawson ES, Persky AM, Price TB, Clarkson PM. Effects of repeated creatine supplementation on muscle, plasma, and urine creatine levels. J Strength Cond Res. 2004 Feb;18(1):162-7. doi: 10.1519/1533-4287(2004)018<0162:eorcso>;2. PMID: 14971966.
  4. Preen D, Dawson B, Goodman C, Beilby J, Ching S. Creatine supplementation: a comparison of loading and maintenance protocols on creatine uptake by human skeletal muscle. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):97-111. doi: 10.1123/ijsnem.13.1.97. PMID: 12660409.

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